South Brisbane has a rich and diverse history that spans thousands of years. The area is the traditional land of the Jagera and Turrbal peoples, who have been the custodians of this land for over 40,000 years. The Brisbane River, known as Maiwar in the language of the Turrbal people, has always been central to the area's identity and development.

European settlement began in the 1840s, with South Brisbane quickly developing into an important commercial and transport hub. The construction of the Victoria Bridge in 1874 connected South Brisbane to the north side, accelerating the area's growth and importance.

By the late 19th century, South Brisbane had become a thriving municipality with its own Town Hall (now home to the Queensland Conservatorium). The area has weathered floods, economic changes, and urban renewal to emerge as one of Brisbane's most culturally significant neighbourhoods.

South Brisbane is one of Queensland's most diverse and dynamic communities. The electorate encompasses several distinct neighborhoods including South Brisbane, West End, Highgate Hill, Dutton Park, and parts of Woolloongabba.

The area is characterized by its multicultural population, with significant Greek, Vietnamese, Chinese, and Indigenous communities contributing to its rich cultural tapestry. This diversity is celebrated through numerous cultural festivals, markets, and community events throughout the year.

South Brisbane has a younger demographic than the Queensland average, with many students, young professionals, and creative workers calling the area home. The electorate also has a mix of long-term residents and new arrivals, creating a vibrant community atmosphere.

The area is known for its progressive values, strong community engagement, and active participation in social and environmental initiatives. Local community groups and organisations play a vital role in shaping the area's identity and future.